Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
casrExtracellular calcium-sensing receptor. (1031 aa)    
Predicted Functional Partners:
plcb1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.914
plcb2
Phosphoinositide phospholipase C.
     
 0.914
LOC103171709
Phosphoinositide phospholipase C.
     
 0.909
LOC103179178
Vomeronasal type-1 receptor.
      
 0.682
gcat
Aminotran_1_2 domain-containing protein.
      
 0.508
ENSCMIP00000005060
NDK domain-containing protein; Belongs to the NDK family.
    
   0.443
LOC103187939
Uncharacterized protein; Belongs to the NDK family.
    
   0.443
adcy1
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.410
adcy2
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.410
adcy8
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.410
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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