Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbxl12Uncharacterized protein. (322 aa)    
Predicted Functional Partners:
cul1
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.985
skp1
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.893
LOC103182116
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.893
rbx1
RING-type domain-containing protein.
    
 0.861
fbxw8
Uncharacterized protein.
    
 0.709
srp72
Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.
      
 0.687
cul3
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.616
pif1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
   
  
 0.535
styx
Uncharacterized protein.
    
   0.522
rnf7
RING-box protein 2-like protein.
    
 0.503
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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