atg4d protein (Callorhinchus milii) - STRING interaction network

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atg4d

Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (512 aa)

Predicted Functional Partners:

gabarapl2

0.987

map1lc3a

0.974

LOC103179261

0.972

map1lc3b

0.762

atg3

0.755

atg7

0.674

ENSCMIP00000035149

0.605

ulk1

0.605

ulk2

0.605

becn1

0.577

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCMIP00000035149	LOC103179261	ENSCMIP00000035149	ENSCMIP00000016534	Protein kinase domain-containing protein.	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	0.831
ENSCMIP00000035149	atg3	ENSCMIP00000035149	ENSCMIP00000027669	Protein kinase domain-containing protein.	Autophagy-related protein 3.	0.823
ENSCMIP00000035149	atg4d	ENSCMIP00000035149	ENSCMIP00000006897	Protein kinase domain-containing protein.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.605
ENSCMIP00000035149	atg7	ENSCMIP00000035149	ENSCMIP00000009203	Protein kinase domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.705
ENSCMIP00000035149	becn1	ENSCMIP00000035149	ENSCMIP00000018475	Protein kinase domain-containing protein.	Uncharacterized protein.	0.908
ENSCMIP00000035149	gabarapl2	ENSCMIP00000035149	ENSCMIP00000034498	Protein kinase domain-containing protein.	Uncharacterized protein.	0.891
ENSCMIP00000035149	map1lc3a	ENSCMIP00000035149	ENSCMIP00000026156	Protein kinase domain-containing protein.	Uncharacterized protein.	0.749
ENSCMIP00000035149	map1lc3b	ENSCMIP00000035149	ENSCMIP00000036315	Protein kinase domain-containing protein.	Uncharacterized protein.	0.749
ENSCMIP00000035149	ulk1	ENSCMIP00000035149	ENSCMIP00000035152	Protein kinase domain-containing protein.	DUF3543 domain-containing protein.	0.900
LOC103179261	ENSCMIP00000035149	ENSCMIP00000016534	ENSCMIP00000035149	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	Protein kinase domain-containing protein.	0.831
LOC103179261	atg3	ENSCMIP00000016534	ENSCMIP00000027669	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	Autophagy-related protein 3.	0.997
LOC103179261	atg4d	ENSCMIP00000016534	ENSCMIP00000006897	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.972
LOC103179261	atg7	ENSCMIP00000016534	ENSCMIP00000009203	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.997
LOC103179261	becn1	ENSCMIP00000016534	ENSCMIP00000018475	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	Uncharacterized protein.	0.969
LOC103179261	gabarapl2	ENSCMIP00000016534	ENSCMIP00000034498	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	Uncharacterized protein.	0.974
LOC103179261	map1lc3a	ENSCMIP00000016534	ENSCMIP00000026156	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	Uncharacterized protein.	0.946
LOC103179261	map1lc3b	ENSCMIP00000016534	ENSCMIP00000036315	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	Uncharacterized protein.	0.471
LOC103179261	ulk1	ENSCMIP00000016534	ENSCMIP00000035152	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	DUF3543 domain-containing protein.	0.831
LOC103179261	ulk2	ENSCMIP00000016534	ENSCMIP00000046939	Microtubule-associated proteins 1A/1B light chain 3C-like protein.	Unc-51-like kinase 2.	0.831
atg3	ENSCMIP00000035149	ENSCMIP00000027669	ENSCMIP00000035149	Autophagy-related protein 3.	Protein kinase domain-containing protein.	0.823

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