| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSCMIP00000003431 | apex2 | ENSCMIP00000003431 | ENSCMIP00000036231 | XRCC1_N domain-containing protein. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.690 |
| ENSCMIP00000003431 | ercc4 | ENSCMIP00000003431 | ENSCMIP00000019357 | XRCC1_N domain-containing protein. | ERCC4 domain-containing protein. | 0.420 |
| ENSCMIP00000003431 | fancm | ENSCMIP00000003431 | ENSCMIP00000005855 | XRCC1_N domain-containing protein. | Uncharacterized protein. | 0.591 |
| ENSCMIP00000003431 | lig3 | ENSCMIP00000003431 | ENSCMIP00000028093 | XRCC1_N domain-containing protein. | DNA ligase. | 0.998 |
| ENSCMIP00000003431 | lig4 | ENSCMIP00000003431 | ENSCMIP00000010015 | XRCC1_N domain-containing protein. | DNA ligase. | 0.953 |
| ENSCMIP00000003431 | tdp1 | ENSCMIP00000003431 | ENSCMIP00000007379 | XRCC1_N domain-containing protein. | Uncharacterized protein. | 0.689 |
| ENSCMIP00000003431 | top1 | ENSCMIP00000003431 | ENSCMIP00000037518 | XRCC1_N domain-containing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.434 |
| ENSCMIP00000003431 | top1mt | ENSCMIP00000003431 | ENSCMIP00000027673 | XRCC1_N domain-containing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.433 |
| ENSCMIP00000003431 | xrcc5 | ENSCMIP00000003431 | ENSCMIP00000038307 | XRCC1_N domain-containing protein. | Ku domain-containing protein. | 0.657 |
| ENSCMIP00000003431 | xrcc6 | ENSCMIP00000003431 | ENSCMIP00000009666 | XRCC1_N domain-containing protein. | Uncharacterized protein. | 0.813 |
| apex2 | ENSCMIP00000003431 | ENSCMIP00000036231 | ENSCMIP00000003431 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | XRCC1_N domain-containing protein. | 0.690 |
| apex2 | ercc4 | ENSCMIP00000036231 | ENSCMIP00000019357 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | ERCC4 domain-containing protein. | 0.870 |
| apex2 | fancm | ENSCMIP00000036231 | ENSCMIP00000005855 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Uncharacterized protein. | 0.799 |
| apex2 | lig3 | ENSCMIP00000036231 | ENSCMIP00000028093 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA ligase. | 0.846 |
| apex2 | lig4 | ENSCMIP00000036231 | ENSCMIP00000010015 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA ligase. | 0.817 |
| apex2 | tdp1 | ENSCMIP00000036231 | ENSCMIP00000007379 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Uncharacterized protein. | 0.686 |
| apex2 | top1 | ENSCMIP00000036231 | ENSCMIP00000037518 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.455 |
| apex2 | top1mt | ENSCMIP00000036231 | ENSCMIP00000027673 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.455 |
| apex2 | xrcc5 | ENSCMIP00000036231 | ENSCMIP00000038307 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Ku domain-containing protein. | 0.605 |
| ercc4 | ENSCMIP00000003431 | ENSCMIP00000019357 | ENSCMIP00000003431 | ERCC4 domain-containing protein. | XRCC1_N domain-containing protein. | 0.420 |