Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Znf521Uncharacterized protein. (1227 aa)    
Predicted Functional Partners:
ENSCMIP00000007498
Uncharacterized protein.
 
     0.917
znf536
Uncharacterized protein.
    
 
 0.641
mbd3
MBD domain-containing protein.
    
  0.609
usp7
Uncharacterized protein; Belongs to the peptidase C19 family.
    
 
 0.604
eif3f
Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
    
 0.577
smad4
Mothers against decapentaplegic homolog.
    
 0.571
rbbp7
Histone-binding protein RBBP7.
    
  0.557
rbbp4
WD_REPEATS_REGION domain-containing protein.
    
  0.557
hdac3
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.509
pax6
Uncharacterized protein.
    
 0.473
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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