Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mapk8Mitogen-activated protein kinase. (452 aa)    
Predicted Functional Partners:
mapk9
Mitogen-activated protein kinase.
  
0.998
jun
Jun domain-containing protein.
   
 0.998
map2k4
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
0.997
fos
Proto-oncogene c-Fos.
   
 0.992
map3k1
Uncharacterized protein.
    
0.991
mapk8ip1
Uncharacterized protein.
   
 0.989
bcl2l1
BH4_2 domain-containing protein.
    
 0.981
nfatc3
RHD domain-containing protein.
    
 0.973
jund
BZIP domain-containing protein.
   
 0.969
rac1
Uncharacterized protein.
   
 0.969
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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