STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tp73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (626 aa)    
Predicted Functional Partners:
ENSCMIP00000026210
Uncharacterized protein.
    
 0.756
chek2
Uncharacterized protein.
    
 0.732
Pwwp2a
PWWP domain-containing protein 2A.
   
 0.712
atm
Non-specific serine/threonine protein kinase.
   
 0.712
mdm2
RING-type domain-containing protein; Belongs to the MDM2/MDM4 family.
    
 0.711
rps27a
Ubiquitin-like domain-containing protein.
    
  0.703
chek1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.680
yap1
WW domain-containing protein.
    
 0.662
wwtr1
Uncharacterized protein.
    
 0.662
bard1
Uncharacterized protein.
    
 0.656
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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