Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pnpla4PNPLA domain-containing protein. (254 aa)    
Predicted Functional Partners:
retsat
Amino_oxidase domain-containing protein.
     
 0.933
med14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
 0.918
dgat1
O-acyltransferase.
     
 0.911
rdh13
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.911
LOC103185953
Uncharacterized protein; Belongs to the membrane-bound acyltransferase family.
     
 0.911
dhrs9
Dehydrogenase/reductase SDR family member 9-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.911
rdh12
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.911
LOC103187903
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.911
LOC103186371
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.911
LOC103188743
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
     
 0.909
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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