Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSCMIP00000007935Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (362 aa)    
Predicted Functional Partners:
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.970
map2k7
Protein kinase domain-containing protein.
    
 
 0.622
fos
Proto-oncogene c-Fos.
   
 
 0.577
mapk8
Mitogen-activated protein kinase.
    
 0.558
mapk10
Mitogen-activated protein kinase.
    
 0.558
mapk9
Mitogen-activated protein kinase.
    
 0.558
jun
Jun domain-containing protein.
   
 0.544
irf2
IRF tryptophan pentad repeat domain-containing protein.
    
 0.538
fosl2
BZIP domain-containing protein.
   
 
 0.492
LOC103188730
Serine/threonine-protein kinase SIK2-like protein.
   
 
 0.490
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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