Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pak3Protein kinase domain-containing protein. (81 aa)    
Predicted Functional Partners:
LOC103172351
Protein kinase domain-containing protein.
 
 
  0.982
cdc42
Cell division control protein 42-like protein.
   
 0.909
LOC103172337
CRIB domain-containing protein.
 
      0.899
pak2
Non-specific serine/threonine protein kinase.
   
  0.828
arhgef6
Uncharacterized protein.
   
 0.767
arhgef7
Uncharacterized protein.
   
 0.767
plekhn1
Uncharacterized protein.
   
 0.767
git1
Uncharacterized protein.
    
 0.744
git2
Uncharacterized protein.
    
 0.744
nck1
Cytoplasmic protein.
    
 0.695
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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