STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf1Interferon regulatory factor. (336 aa)    
Predicted Functional Partners:
mdm2
RING-type domain-containing protein; Belongs to the MDM2/MDM4 family.
    
 0.934
ep300
Uncharacterized protein.
    
 0.803
irf2
IRF tryptophan pentad repeat domain-containing protein.
  
0.783
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.764
irf4
IRF tryptophan pentad repeat domain-containing protein.
  
0.739
stat1
Signal transducer and activator of transcription.
   
 0.695
irf7
IRF tryptophan pentad repeat domain-containing protein.
  
  
0.688
jun
Jun domain-containing protein.
   
 0.620
crebbp
Uncharacterized protein.
    
 0.608
Socs1
Uncharacterized protein.
   
 
 0.592
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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