STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103172382Uncharacterized protein. (273 aa)    
Predicted Functional Partners:
LOC103180179
3 beta-hydroxysteroid dehydrogenase; Belongs to the 3-beta-HSD family.
   
 0.951
hsd17b3
Testosterone 17-beta-dehydrogenase 3.
   
 0.944
LOC103188165
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
   
 0.927
LOC103191276
Corticosteroid 11-beta-dehydrogenase isozyme 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.922
LOC103186779
Uncharacterized protein.
   
 
 0.921
srd5a1
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
     
 0.918
srd5a2
S5A_REDUCTASE domain-containing protein.
     
 0.918
LOC103185125
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 0.915
srd5a3
S5A_REDUCTASE domain-containing protein.
     
 0.910
ENSCMIP00000008488
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
 0.906
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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