LOC103191437 protein (Callorhinchus milii) - STRING interaction network

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LOC103191437

Indoleamine 2,3-dioxygenase 2. (407 aa)

Predicted Functional Partners:

tdo2

0.991

kynu

0.971

afmid

0.971

LOC103178928

0.942

ddc

0.935

tph2

0.928

tph1

0.928

LOC103177252

0.925

maob

0.925

asmt

0.908

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103177252	LOC103191437	ENSCMIP00000007745	ENSCMIP00000008449	Amine oxidase.	Indoleamine 2,3-dioxygenase 2.	0.925
LOC103177252	ddc	ENSCMIP00000007745	ENSCMIP00000043516	Amine oxidase.	Aromatic-L-amino-acid decarboxylase.	0.937
LOC103177252	maob	ENSCMIP00000007745	ENSCMIP00000026484	Amine oxidase.	Amine oxidase.	0.901
LOC103178928	LOC103191437	ENSCMIP00000034217	ENSCMIP00000008449	Uncharacterized protein; Belongs to the cytochrome P450 family.	Indoleamine 2,3-dioxygenase 2.	0.942
LOC103178928	asmt	ENSCMIP00000034217	ENSCMIP00000038766	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.911
LOC103191437	LOC103177252	ENSCMIP00000008449	ENSCMIP00000007745	Indoleamine 2,3-dioxygenase 2.	Amine oxidase.	0.925
LOC103191437	LOC103178928	ENSCMIP00000008449	ENSCMIP00000034217	Indoleamine 2,3-dioxygenase 2.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.942
LOC103191437	afmid	ENSCMIP00000008449	ENSCMIP00000047801	Indoleamine 2,3-dioxygenase 2.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.971
LOC103191437	asmt	ENSCMIP00000008449	ENSCMIP00000038766	Indoleamine 2,3-dioxygenase 2.	Uncharacterized protein.	0.908
LOC103191437	ddc	ENSCMIP00000008449	ENSCMIP00000043516	Indoleamine 2,3-dioxygenase 2.	Aromatic-L-amino-acid decarboxylase.	0.935
LOC103191437	kynu	ENSCMIP00000008449	ENSCMIP00000023401	Indoleamine 2,3-dioxygenase 2.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.971
LOC103191437	maob	ENSCMIP00000008449	ENSCMIP00000026484	Indoleamine 2,3-dioxygenase 2.	Amine oxidase.	0.925
LOC103191437	tdo2	ENSCMIP00000008449	ENSCMIP00000023057	Indoleamine 2,3-dioxygenase 2.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.991
LOC103191437	tph1	ENSCMIP00000008449	ENSCMIP00000025709	Indoleamine 2,3-dioxygenase 2.	Uncharacterized protein.	0.928
LOC103191437	tph2	ENSCMIP00000008449	ENSCMIP00000002099	Indoleamine 2,3-dioxygenase 2.	Uncharacterized protein.	0.928
afmid	LOC103191437	ENSCMIP00000047801	ENSCMIP00000008449	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Indoleamine 2,3-dioxygenase 2.	0.971
afmid	ddc	ENSCMIP00000047801	ENSCMIP00000043516	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Aromatic-L-amino-acid decarboxylase.	0.910
afmid	kynu	ENSCMIP00000047801	ENSCMIP00000023401	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.988
afmid	tdo2	ENSCMIP00000047801	ENSCMIP00000023057	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.986
asmt	LOC103178928	ENSCMIP00000038766	ENSCMIP00000034217	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.911