Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCMIP00000008488Sulfotransferase; Belongs to the sulfotransferase 1 family. (308 aa)    
Predicted Functional Partners:
LOC103180179
3 beta-hydroxysteroid dehydrogenase; Belongs to the 3-beta-HSD family.
   
 
 0.948
LOC103180710
Uncharacterized protein.
   
 
 0.922
sts
Sulfatase domain-containing protein.
   
 
 0.914
LOC103177103
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.911
LOC103180767
Uncharacterized protein.
     
 0.911
LOC103185125
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.908
LOC103188165
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
     
 0.905
LOC103185645
Sulfotransferase; Belongs to the sulfotransferase 1 family.
  
  
 
0.903
LOC103180618
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.903
dhcr7
Uncharacterized protein.
     
 0.831
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.