Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppp4r4Uncharacterized protein. (743 aa)    
Predicted Functional Partners:
ppp4c
Serine/threonine-protein phosphatase.
   
 0.969
ptpa
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
 
 0.752
ppp4r2
Uncharacterized protein.
    
 
 0.743
ppme1
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.
    
 0.714
LOC103191459
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
   
 0.711
ppp2r2b
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
   
 0.711
ppp2ca
Serine/threonine-protein phosphatase.
   
 0.709
LOC103186729
Serine/threonine-protein phosphatase.
   
 0.709
ppp2r3a
Uncharacterized protein.
    
 0.704
LOC103177106
EF-hand domain-containing protein.
    
 0.704
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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