Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
frkTyrosine-protein kinase. (517 aa)    
Predicted Functional Partners:
mipol1
Uncharacterized protein.
   
    0.962
LOC103177174
Uncharacterized protein.
    
 0.775
pten
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.775
sh2d1a
SH2 domain-containing protein 1A-like protein.
   
 0.720
rapgef1
Uncharacterized protein.
    
 0.715
ugp2
UTP--glucose-1-phosphate uridylyltransferase.
    
 
 0.693
matk
Tyrosine-protein kinase.
   
 0.671
csk
Tyrosine-protein kinase.
   
 0.671
ENSCMIP00000043212
Sema domain-containing protein.
 
 
  0.671
gpi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
      
 0.646
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
Server load: low (28%) [HD]