Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
kcnj1ATP-sensitive inward rectifier potassium channel 1. (369 aa)    
Predicted Functional Partners:
bsnd
Uncharacterized protein.
   
  
 0.764
kcnj16
Uncharacterized protein.
   
 
  0.736
fam131c
Uncharacterized protein.
      
 0.675
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.668
miox
Uncharacterized protein.
   
  
 0.648
scnn1b
Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.554
slc35b1
Uncharacterized protein.
      
 0.552
slc26a10
STAS domain-containing protein.
   
  
 0.522
kcne2
Uncharacterized protein.
   
  
 0.521
wdr38
WD_REPEATS_REGION domain-containing protein.
      
 0.516
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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