| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC103183128 | LOC103188631 | ENSCMIP00000009239 | ENSCMIP00000005674 | Cytosolic 5'-nucleotidase 1B-like protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.916 |
| LOC103183128 | LOC103190184 | ENSCMIP00000009239 | ENSCMIP00000009807 | Cytosolic 5'-nucleotidase 1B-like protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.914 |
| LOC103183128 | adss2 | ENSCMIP00000009239 | ENSCMIP00000046669 | Cytosolic 5'-nucleotidase 1B-like protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.912 |
| LOC103183128 | ak3 | ENSCMIP00000009239 | ENSCMIP00000003975 | Cytosolic 5'-nucleotidase 1B-like protein. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.915 |
| LOC103183128 | aprt | ENSCMIP00000009239 | ENSCMIP00000034689 | Cytosolic 5'-nucleotidase 1B-like protein. | Pribosyltran domain-containing protein. | 0.911 |
| LOC103183128 | guk1 | ENSCMIP00000009239 | ENSCMIP00000019424 | Cytosolic 5'-nucleotidase 1B-like protein. | Guanylate kinase. | 0.920 |
| LOC103183128 | itpa | ENSCMIP00000009239 | ENSCMIP00000045591 | Cytosolic 5'-nucleotidase 1B-like protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.914 |
| LOC103183128 | nt5e | ENSCMIP00000009239 | ENSCMIP00000015555 | Cytosolic 5'-nucleotidase 1B-like protein. | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | 0.914 |
| LOC103183128 | nudt12 | ENSCMIP00000009239 | ENSCMIP00000043252 | Cytosolic 5'-nucleotidase 1B-like protein. | Uncharacterized protein. | 0.911 |
| LOC103183128 | tyms | ENSCMIP00000009239 | ENSCMIP00000038564 | Cytosolic 5'-nucleotidase 1B-like protein. | Thymidylat_synt domain-containing protein. | 0.920 |
| LOC103188631 | LOC103183128 | ENSCMIP00000005674 | ENSCMIP00000009239 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Cytosolic 5'-nucleotidase 1B-like protein. | 0.916 |
| LOC103188631 | LOC103190184 | ENSCMIP00000005674 | ENSCMIP00000009807 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.482 |
| LOC103188631 | aprt | ENSCMIP00000005674 | ENSCMIP00000034689 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Pribosyltran domain-containing protein. | 0.962 |
| LOC103188631 | nt5e | ENSCMIP00000005674 | ENSCMIP00000015555 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | 0.955 |
| LOC103190184 | LOC103183128 | ENSCMIP00000009807 | ENSCMIP00000009239 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Cytosolic 5'-nucleotidase 1B-like protein. | 0.914 |
| LOC103190184 | LOC103188631 | ENSCMIP00000009807 | ENSCMIP00000005674 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.482 |
| LOC103190184 | adss2 | ENSCMIP00000009807 | ENSCMIP00000046669 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.955 |
| LOC103190184 | itpa | ENSCMIP00000009807 | ENSCMIP00000045591 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.933 |
| LOC103190184 | nt5e | ENSCMIP00000009807 | ENSCMIP00000015555 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | 0.933 |
| adss2 | LOC103183128 | ENSCMIP00000046669 | ENSCMIP00000009239 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Cytosolic 5'-nucleotidase 1B-like protein. | 0.912 |