notch2 protein (Callorhinchus milii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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Experiments

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Textmining

[Homology]

Score

notch2

Uncharacterized protein. (2440 aa)

Predicted Functional Partners:

rbpj

0.981

dll1

0.969

rbpjl

0.940

psen1

0.934

dtx1

0.920

dtx2

0.920

LOC103172250

0.915

numb

0.915

psen2

0.914

LOC103189782

0.913

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103172250	notch2	ENSCMIP00000007092	ENSCMIP00000009481	PID domain-containing protein.	Uncharacterized protein.	0.915
LOC103172250	numb	ENSCMIP00000007092	ENSCMIP00000044469	PID domain-containing protein.	PID domain-containing protein.	0.902
LOC103189782	notch2	ENSCMIP00000014331	ENSCMIP00000009481	Beta-1,3-N-acetylglucosaminyltransferase.	Uncharacterized protein.	0.913
dll1	notch2	ENSCMIP00000006436	ENSCMIP00000009481	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.969
dll1	rbpj	ENSCMIP00000006436	ENSCMIP00000024936	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.653
dll1	rbpjl	ENSCMIP00000006436	ENSCMIP00000040615	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.450
dtx1	notch2	ENSCMIP00000015353	ENSCMIP00000009481	Uncharacterized protein.	Uncharacterized protein.	0.920
dtx2	notch2	ENSCMIP00000028581	ENSCMIP00000009481	RING-type domain-containing protein.	Uncharacterized protein.	0.920
notch2	LOC103172250	ENSCMIP00000009481	ENSCMIP00000007092	Uncharacterized protein.	PID domain-containing protein.	0.915
notch2	LOC103189782	ENSCMIP00000009481	ENSCMIP00000014331	Uncharacterized protein.	Beta-1,3-N-acetylglucosaminyltransferase.	0.913
notch2	dll1	ENSCMIP00000009481	ENSCMIP00000006436	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.969
notch2	dtx1	ENSCMIP00000009481	ENSCMIP00000015353	Uncharacterized protein.	Uncharacterized protein.	0.920
notch2	dtx2	ENSCMIP00000009481	ENSCMIP00000028581	Uncharacterized protein.	RING-type domain-containing protein.	0.920
notch2	numb	ENSCMIP00000009481	ENSCMIP00000044469	Uncharacterized protein.	PID domain-containing protein.	0.915
notch2	psen1	ENSCMIP00000009481	ENSCMIP00000044514	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.934
notch2	psen2	ENSCMIP00000009481	ENSCMIP00000005625	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.914
notch2	rbpj	ENSCMIP00000009481	ENSCMIP00000024936	Uncharacterized protein.	Uncharacterized protein.	0.981
notch2	rbpjl	ENSCMIP00000009481	ENSCMIP00000040615	Uncharacterized protein.	Uncharacterized protein.	0.940
numb	LOC103172250	ENSCMIP00000044469	ENSCMIP00000007092	PID domain-containing protein.	PID domain-containing protein.	0.902
numb	notch2	ENSCMIP00000044469	ENSCMIP00000009481	PID domain-containing protein.	Uncharacterized protein.	0.915