Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
notch2Uncharacterized protein. (2440 aa)    
Predicted Functional Partners:
rbpj
Uncharacterized protein.
    
 0.987
dll1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.966
jag2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.963
LOC103186455
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.959
LOC103190052
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.959
notch1
Uncharacterized protein.
  
0.946
psen1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.937
dtx1
Uncharacterized protein.
    
 0.931
dtx2
RING-type domain-containing protein.
    
 0.931
rbpjl
Uncharacterized protein.
    
 0.931
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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