Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
map3k4Protein kinase domain-containing protein. (1635 aa)    
Predicted Functional Partners:
gadd45g
Growth arrest and DNA-damage-inducible, gamma.
    
 0.988
LOC103185143
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
0.977
Gadd45a
Ribosomal_L7Ae domain-containing protein.
    
 0.959
gadd45b
Ribosomal_L7Ae domain-containing protein.
    
 0.959
chac2
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
      
 0.794
cdc42
Cell division control protein 42-like protein.
    
 
 0.786
ENSCMIP00000046748
Protein kinase domain-containing protein.
    
 
 0.784
asb3
Uncharacterized protein.
    
 
 0.773
dennd11
UDENN domain-containing protein.
    
   0.764
erlec1
Endoplasmic reticulum lectin 1.
      
 0.761
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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