Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spidrUncharacterized protein. (949 aa)    
Predicted Functional Partners:
zswim7
SWIM-type domain-containing protein.
    
   0.919
unc79
Uncharacterized protein.
      
 0.791
LOC103190668
Phospholipase A(2).
    
   0.769
mcm4
DNA helicase; Belongs to the MCM family.
      
 0.768
prkdc
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
      
 0.749
ENSCMIP00000004361
Uncharacterized protein; Belongs to the AAA ATPase family.
    
 0.736
spast
Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...]
    
 0.736
ENSCMIP00000016909
AAA domain-containing protein; Belongs to the AAA ATPase family.
    
 0.736
fignl1
AAA domain-containing protein; Belongs to the AAA ATPase family.
    
 0.736
dhfr
DHFR domain-containing protein.
      
 0.729
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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