Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zic1Uncharacterized protein. (492 aa)    
Predicted Functional Partners:
LOC103183084
POU domain protein.
    
 0.541
prdm11
SET domain-containing protein.
    
 
 0.502
sox2
Transcription factor SOX-2.
   
 0.496
Rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
   
  
 0.486
svep1
Uncharacterized protein.
    
 0.444
gpr27
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
 
 
 0.435
mysm1
Uncharacterized protein.
   
  0.425
ENSCMIP00000005060
NDK domain-containing protein; Belongs to the NDK family.
    
 0.420
LOC103187939
Uncharacterized protein; Belongs to the NDK family.
    
 0.420
Pax3
Uncharacterized protein.
   
 0.414
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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