pak5 protein (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

pak5

Protein kinase domain-containing protein. (373 aa)

Predicted Functional Partners:

Pak5

0.900

LOC103172337

0.858

cdc42

0.841

inka1

0.787

ENSCMIP00000004387

0.672

rac1

0.630

LOC103191021

0.630

rac3

0.630

nck1

0.628

nck2

0.628

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCMIP00000004387	pak5	ENSCMIP00000004387	ENSCMIP00000011343	Uncharacterized protein.	Protein kinase domain-containing protein.	0.672
LOC103172337	LOC103191021	ENSCMIP00000007887	ENSCMIP00000021483	CRIB domain-containing protein.	Uncharacterized protein.	0.680
LOC103172337	Pak5	ENSCMIP00000007887	ENSCMIP00000011352	CRIB domain-containing protein.	CRIB domain-containing protein.	0.416
LOC103172337	cdc42	ENSCMIP00000007887	ENSCMIP00000003700	CRIB domain-containing protein.	Cell division control protein 42-like protein.	0.909
LOC103172337	inka1	ENSCMIP00000007887	ENSCMIP00000043834	CRIB domain-containing protein.	FAM212 domain-containing protein.	0.412
LOC103172337	nck1	ENSCMIP00000007887	ENSCMIP00000038494	CRIB domain-containing protein.	Cytoplasmic protein.	0.695
LOC103172337	nck2	ENSCMIP00000007887	ENSCMIP00000041157	CRIB domain-containing protein.	Cytoplasmic protein.	0.695
LOC103172337	pak5	ENSCMIP00000007887	ENSCMIP00000011343	CRIB domain-containing protein.	Protein kinase domain-containing protein.	0.858
LOC103172337	rac1	ENSCMIP00000007887	ENSCMIP00000014308	CRIB domain-containing protein.	Uncharacterized protein.	0.680
LOC103172337	rac3	ENSCMIP00000007887	ENSCMIP00000044273	CRIB domain-containing protein.	Uncharacterized protein.	0.680
LOC103191021	LOC103172337	ENSCMIP00000021483	ENSCMIP00000007887	Uncharacterized protein.	CRIB domain-containing protein.	0.680
LOC103191021	Pak5	ENSCMIP00000021483	ENSCMIP00000011352	Uncharacterized protein.	CRIB domain-containing protein.	0.961
LOC103191021	cdc42	ENSCMIP00000021483	ENSCMIP00000003700	Uncharacterized protein.	Cell division control protein 42-like protein.	0.836
LOC103191021	nck1	ENSCMIP00000021483	ENSCMIP00000038494	Uncharacterized protein.	Cytoplasmic protein.	0.577
LOC103191021	nck2	ENSCMIP00000021483	ENSCMIP00000041157	Uncharacterized protein.	Cytoplasmic protein.	0.577
LOC103191021	pak5	ENSCMIP00000021483	ENSCMIP00000011343	Uncharacterized protein.	Protein kinase domain-containing protein.	0.630
LOC103191021	rac1	ENSCMIP00000021483	ENSCMIP00000014308	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC103191021	rac3	ENSCMIP00000021483	ENSCMIP00000044273	Uncharacterized protein.	Uncharacterized protein.	0.901
Pak5	LOC103172337	ENSCMIP00000011352	ENSCMIP00000007887	CRIB domain-containing protein.	CRIB domain-containing protein.	0.416
Pak5	LOC103191021	ENSCMIP00000011352	ENSCMIP00000021483	CRIB domain-containing protein.	Uncharacterized protein.	0.961