yap1 protein (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

yap1

WW domain-containing protein. (522 aa)

Predicted Functional Partners:

lats1

0.947

amotl2

0.927

ywhae

0.916

tead2

0.906

amot

0.905

lats2

0.899

stk3

0.896

stk4

0.896

tead1

0.887

tead3

0.887

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
amot	amotl2	ENSCMIP00000040143	ENSCMIP00000026205	Angiomotin_C domain-containing protein.	Angiomotin_C domain-containing protein.	0.922
amot	lats1	ENSCMIP00000040143	ENSCMIP00000017802	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.918
amot	lats2	ENSCMIP00000040143	ENSCMIP00000022074	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.852
amot	stk3	ENSCMIP00000040143	ENSCMIP00000005867	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.588
amot	stk4	ENSCMIP00000040143	ENSCMIP00000018140	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.588
amot	yap1	ENSCMIP00000040143	ENSCMIP00000011714	Angiomotin_C domain-containing protein.	WW domain-containing protein.	0.905
amot	ywhae	ENSCMIP00000040143	ENSCMIP00000030913	Angiomotin_C domain-containing protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.658
amotl2	amot	ENSCMIP00000026205	ENSCMIP00000040143	Angiomotin_C domain-containing protein.	Angiomotin_C domain-containing protein.	0.922
amotl2	lats1	ENSCMIP00000026205	ENSCMIP00000017802	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.929
amotl2	lats2	ENSCMIP00000026205	ENSCMIP00000022074	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.915
amotl2	stk3	ENSCMIP00000026205	ENSCMIP00000005867	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.549
amotl2	stk4	ENSCMIP00000026205	ENSCMIP00000018140	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.549
amotl2	tead1	ENSCMIP00000026205	ENSCMIP00000002276	Angiomotin_C domain-containing protein.	TEA domain-containing protein.	0.402
amotl2	tead3	ENSCMIP00000026205	ENSCMIP00000011810	Angiomotin_C domain-containing protein.	Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.	0.402
amotl2	yap1	ENSCMIP00000026205	ENSCMIP00000011714	Angiomotin_C domain-containing protein.	WW domain-containing protein.	0.927
amotl2	ywhae	ENSCMIP00000026205	ENSCMIP00000030913	Angiomotin_C domain-containing protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.651
lats1	amot	ENSCMIP00000017802	ENSCMIP00000040143	Uncharacterized protein.	Angiomotin_C domain-containing protein.	0.918
lats1	amotl2	ENSCMIP00000017802	ENSCMIP00000026205	Uncharacterized protein.	Angiomotin_C domain-containing protein.	0.929
lats1	stk3	ENSCMIP00000017802	ENSCMIP00000005867	Uncharacterized protein.	Uncharacterized protein.	0.855
lats1	stk4	ENSCMIP00000017802	ENSCMIP00000018140	Uncharacterized protein.	Uncharacterized protein.	0.855