STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hdac3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (425 aa)    
Predicted Functional Partners:
leo1
RNA polymerase-associated protein LEO1.
   
 0.963
arid4a
ARID domain-containing protein.
   
 0.957
arid4b
ARID domain-containing protein.
   
 0.957
ncor1
Uncharacterized protein.
    
 0.886
ENSCMIP00000033330
Uncharacterized protein.
    
 0.886
Ncor2
Uncharacterized protein.
    
 0.886
suds3
Sin3 histone deacetylase corepressor complex component SDS3-like protein.
    
 0.872
tbl1xr1
Uncharacterized protein.
   
 0.869
LOC103177163
Uncharacterized protein.
   
 0.869
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 0.827
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.