STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103185457Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (299 aa)    
Predicted Functional Partners:
smc5
AAA_23 domain-containing protein.
   
 0.983
nsmce1
RING-type domain-containing protein.
   
 0.981
nsmce2
SP-RING-type domain-containing protein.
    
 0.980
smc6
Structural maintenance of chromosomes protein 6.
   
 0.972
nsmce3
MAGE domain-containing protein.
   
 0.908
ENSCMIP00000017237
MAGE domain-containing protein.
   
 0.908
smc3
Structural maintenance of chromosomes protein.
   
 0.841
ENSCMIP00000009725
Uncharacterized protein.
   
 0.797
ENSCMIP00000028564
annotation not available
   
 0.797
pram1
hSH3 domain-containing protein.
   
 0.797
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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