node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC103177420 | bhmt | ENSCMIP00000011368 | ENSCMIP00000045154 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | 0.904 |
LOC103177420 | cbs | ENSCMIP00000011368 | ENSCMIP00000015780 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.952 |
LOC103177420 | cth | ENSCMIP00000011368 | ENSCMIP00000001829 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Uncharacterized protein. | 0.981 |
LOC103177420 | kyat3 | ENSCMIP00000011368 | ENSCMIP00000016550 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Aminotran_1_2 domain-containing protein. | 0.927 |
LOC103177420 | mtr | ENSCMIP00000011368 | ENSCMIP00000030171 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.902 |
afmid | kmo | ENSCMIP00000047801 | ENSCMIP00000011614 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | FAD_binding_3 domain-containing protein. | 0.972 |
afmid | kyat3 | ENSCMIP00000047801 | ENSCMIP00000016550 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Aminotran_1_2 domain-containing protein. | 0.938 |
afmid | kynu | ENSCMIP00000047801 | ENSCMIP00000023401 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.983 |
bhmt | LOC103177420 | ENSCMIP00000045154 | ENSCMIP00000011368 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | 0.904 |
bhmt | cbs | ENSCMIP00000045154 | ENSCMIP00000015780 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.952 |
bhmt | cth | ENSCMIP00000045154 | ENSCMIP00000001829 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Uncharacterized protein. | 0.976 |
bhmt | kyat3 | ENSCMIP00000045154 | ENSCMIP00000016550 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Aminotran_1_2 domain-containing protein. | 0.927 |
bhmt | mtr | ENSCMIP00000045154 | ENSCMIP00000030171 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.953 |
cbs | LOC103177420 | ENSCMIP00000015780 | ENSCMIP00000011368 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | 0.952 |
cbs | bhmt | ENSCMIP00000015780 | ENSCMIP00000045154 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | 0.952 |
cbs | cth | ENSCMIP00000015780 | ENSCMIP00000001829 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Uncharacterized protein. | 0.999 |
cbs | got1 | ENSCMIP00000015780 | ENSCMIP00000035955 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aspartate aminotransferase. | 0.456 |
cbs | got2 | ENSCMIP00000015780 | ENSCMIP00000012577 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aspartate aminotransferase. | 0.433 |
cbs | kyat3 | ENSCMIP00000015780 | ENSCMIP00000016550 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aminotran_1_2 domain-containing protein. | 0.929 |
cbs | mtr | ENSCMIP00000015780 | ENSCMIP00000030171 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.962 |