STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rubcnRUN domain-containing protein. (936 aa)    
Predicted Functional Partners:
ENSCMIP00000018155
Uncharacterized protein.
    
 
 0.964
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 
 0.937
becn1
Uncharacterized protein.
    
 
 0.924
rab7a
Uncharacterized protein.
    
 
 0.830
pik3r4
Uncharacterized protein.
    
 
 0.776
atg14
Uncharacterized protein.
    
 
 0.671
ambra1
WD_REPEATS_REGION domain-containing protein.
   
 
 0.485
atg7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
   
  
 0.465
arl8a
Uncharacterized protein.
    
 
 0.458
arl8b
ADP-ribosylation factor-like protein 8B-A; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.458
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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