STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cacnb4SH3 domain-containing protein. (464 aa)    
Predicted Functional Partners:
cacna2d3
VWFA domain-containing protein.
   
 0.969
Cacna1b
Ion_trans domain-containing protein.
   
 0.957
cacng4
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
     
 0.938
cacng5
Uncharacterized protein.
     
 0.930
LOC103173178
GuKc domain-containing protein.
  
  
 
0.901
cacnb2
SH3 domain-containing protein.
  
  
 
0.901
camk2g
Protein kinase domain-containing protein.
     
 0.900
ppp1cc
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
  0.900
rasgrp1
Uncharacterized protein.
     
  0.900
prkacb
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 
  0.900
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.