STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103187768N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (504 aa)    
Predicted Functional Partners:
gusb
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
  
 0.936
hexb
Beta-hexosaminidase.
   
 0.918
glb1
Uncharacterized protein; Belongs to the glycosyl hydrolase 35 family.
  
 0.911
gns
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
  
  
 
0.901
arsg
Sulfatase domain-containing protein.
  
  
 0.626
ctsz
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 0.611
sgsh
Uncharacterized protein.
  
 
 0.568
LOC103191386
AP-1 complex subunit gamma.
     
 0.559
ap1g1
AP-1 complex subunit gamma.
     
 0.559
med17
Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.554
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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