STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdgfraUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1102 aa)    
Predicted Functional Partners:
grb2
Uncharacterized protein.
   
 0.975
pdgfrb
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
  
0.974
LOC103175503
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.958
pdgfa
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.957
plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.947
plcg1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.947
Shc3
PID domain-containing protein.
   
 0.942
pdgfd
Platelet-derived growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
 0.942
shc4
Uncharacterized protein.
   
 0.942
LOC103191373
Uncharacterized protein.
    
 0.936
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.