emc2 protein (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

emc2

TPR_REGION domain-containing protein. (292 aa)

Predicted Functional Partners:

emc1

0.996

emc6

0.996

emc3

0.995

mmgt1

0.977

emc8

0.974

emc7

0.965

emc10

0.964

dctn4

0.924

derl2

0.701

sec63

0.648

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dctn4	emc1	ENSCMIP00000014518	ENSCMIP00000013006	Uncharacterized protein.	EMC1_C domain-containing protein.	0.953
dctn4	emc2	ENSCMIP00000014518	ENSCMIP00000030159	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.924
dctn4	emc3	ENSCMIP00000014518	ENSCMIP00000044078	Uncharacterized protein.	ER membrane protein complex subunit 3; Belongs to the EMC3 family.	0.949
dctn4	emc6	ENSCMIP00000014518	ENSCMIP00000031677	Uncharacterized protein.	Uncharacterized protein.	0.925
derl2	emc1	ENSCMIP00000027841	ENSCMIP00000013006	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	EMC1_C domain-containing protein.	0.676
derl2	emc2	ENSCMIP00000027841	ENSCMIP00000030159	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	TPR_REGION domain-containing protein.	0.701
derl2	emc3	ENSCMIP00000027841	ENSCMIP00000044078	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ER membrane protein complex subunit 3; Belongs to the EMC3 family.	0.703
derl2	sec63	ENSCMIP00000027841	ENSCMIP00000035852	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Translocation protein SEC63-like protein.	0.686
emc1	dctn4	ENSCMIP00000013006	ENSCMIP00000014518	EMC1_C domain-containing protein.	Uncharacterized protein.	0.953
emc1	derl2	ENSCMIP00000013006	ENSCMIP00000027841	EMC1_C domain-containing protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.676
emc1	emc10	ENSCMIP00000013006	ENSCMIP00000045229	EMC1_C domain-containing protein.	Uncharacterized protein.	0.962
emc1	emc2	ENSCMIP00000013006	ENSCMIP00000030159	EMC1_C domain-containing protein.	TPR_REGION domain-containing protein.	0.996
emc1	emc3	ENSCMIP00000013006	ENSCMIP00000044078	EMC1_C domain-containing protein.	ER membrane protein complex subunit 3; Belongs to the EMC3 family.	0.993
emc1	emc6	ENSCMIP00000013006	ENSCMIP00000031677	EMC1_C domain-containing protein.	Uncharacterized protein.	0.978
emc1	emc7	ENSCMIP00000013006	ENSCMIP00000020408	EMC1_C domain-containing protein.	DUF2012 domain-containing protein.	0.965
emc1	emc8	ENSCMIP00000013006	ENSCMIP00000029947	EMC1_C domain-containing protein.	Uncharacterized protein.	0.972
emc1	mmgt1	ENSCMIP00000013006	ENSCMIP00000009276	EMC1_C domain-containing protein.	Uncharacterized protein.	0.976
emc1	sec63	ENSCMIP00000013006	ENSCMIP00000035852	EMC1_C domain-containing protein.	Translocation protein SEC63-like protein.	0.780
emc10	emc1	ENSCMIP00000045229	ENSCMIP00000013006	Uncharacterized protein.	EMC1_C domain-containing protein.	0.962
emc10	emc2	ENSCMIP00000045229	ENSCMIP00000030159	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.964