STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrrc8aPannexin_like domain-containing protein. (812 aa)    
Predicted Functional Partners:
lrrc8c
Pannexin_like domain-containing protein.
  
 
0.971
lrrc8b
Uncharacterized protein.
  
 
0.799
Lrrc8d
Pannexin_like domain-containing protein.
  
 
0.735
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
      
 0.610
ENSCMIP00000010333
Uncharacterized protein.
    
   0.580
ENSCMIP00000011053
G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.580
adgrl2
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.580
adgrl3
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.580
adgrl1
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.580
ENSCMIP00000047002
SUEL-type lectin domain-containing protein.
    
   0.580
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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