STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrrk2Uncharacterized protein. (2440 aa)    
Predicted Functional Partners:
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 
 0.636
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.625
ENSCMIP00000010333
Uncharacterized protein.
    
   0.580
ENSCMIP00000011053
G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.580
adgrl2
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.580
adgrl3
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.580
adgrl1
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.580
ENSCMIP00000047002
SUEL-type lectin domain-containing protein.
    
   0.580
snca
Alpha-synuclein; Belongs to the synuclein family.
    
 
 0.577
park7
Protein DJ-1-like protein.
    
 
 0.555
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.