STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arih2RBR-type E3 ubiquitin transferase. (493 aa)    
Predicted Functional Partners:
cul5
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 
 0.957
rnf7
RING-box protein 2-like protein.
    
 
 0.894
ube2l3
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.782
ufm1
Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes.
      
 0.673
rnf4
Ring finger protein 4.
    
 
 0.669
rps27a
Ubiquitin-like domain-containing protein.
   
 0.659
LOC103181471
cGMP-dependent protein kinase.
      
 0.653
prkg2
cGMP-dependent protein kinase.
      
 0.653
prkg1
cGMP-dependent protein kinase.
      
 0.653
optn
Optineurin.
    
 0.650
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.