STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pias4E3 SUMO-protein ligase PIAS4. (433 aa)    
Predicted Functional Partners:
ube2i
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.909
atm
Non-specific serine/threonine protein kinase.
   
 0.845
sumo2
Small ubiquitin-related modifier.
    
 0.838
LOC103186049
Small ubiquitin-related modifier.
    
 0.838
sumo1
Small ubiquitin-related modifier.
    
 0.837
LOC103183812
Small ubiquitin-related modifier.
    
 0.837
rnf168
RING-type domain-containing protein.
     
 0.817
Kctd2
Uncharacterized protein.
    
 0.803
rnf8
Uncharacterized protein.
     
 0.779
parp1
Poly [ADP-ribose] polymerase.
    
 0.732
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.