Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLA2G15Phospholipase A2 group XV. (408 aa)    
Predicted Functional Partners:
LPCAT4
Lysophosphatidylcholine acyltransferase 4.
    
 0.931
LYPLA1
Lysophospholipase 1.
     
 0.926
H3AM64_LATCH
Uncharacterized protein.
     
 0.921
H3APZ1_LATCH
Patatin-like phospholipase domain containing 6.
     
 0.921
PNPLA7
Patatin like phospholipase domain containing 7.
     
 0.921
H3B5Q5_LATCH
Lipase_GDSL domain-containing protein.
     
 0.914
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
     
 0.906
LPCAT2
Lysophosphatidylcholine acyltransferase 2.
    
 0.906
LOC102365063
Apolipoprotein A-IV b, tandem duplicate 2.
   
 0.906
PPARD
Peroxisome proliferator activated receptor delta.
     
 0.906
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.