Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102356738USP domain-containing protein; Belongs to the peptidase C19 family. (107 aa)    
Predicted Functional Partners:
USP4
Ubiquitin specific peptidase 4; Belongs to the peptidase C19 family.
 
     0.925
USP11
Ubiquitin specific peptidase 11.
 
 
 0.859
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.843
TGFBR1
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.792
USP14
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.789
SMURF2
E3 ubiquitin-protein ligase.
    
 0.733
SART3
Spliceosome associated factor 3, U4/U6 recycling protein.
    
 
 0.731
PRPF3
Pre-mRNA processing factor 3.
   
 
 0.716
SMAD7
Mothers against decapentaplegic homolog.
    
 0.712
RPS27A
Ribosomal protein S27a.
    
  0.675
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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