Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHCHD7Coiled-coil-helix-coiled-coil-helix domain containing 7. (86 aa)    
Predicted Functional Partners:
FAM163B
Family with sequence similarity 163 member B.
      
 0.828
GNL2
Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
   
  
 0.794
SLC38A10
Solute carrier family 38 member 10.
      
 0.791
NRDE2
NRDE-2, necessary for RNA interference, domain containing.
      
 0.789
PUM2
Pumilio RNA binding family member 2.
    
 
 0.717
PUM1
Pumilio RNA binding family member 1.
    
 
 0.717
GNB3
G protein subunit beta 3.
      
 0.700
LMF1
Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.
      
 0.678
CTSC
Cathepsin C; Belongs to the peptidase C1 family.
      
 0.672
TMEM68
Transmembrane protein 68.
      
 0.657
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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