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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2ZRN5_LATCHUncharacterized protein. (172 aa)    
Predicted Functional Partners:
CREB5
cAMP responsive element binding protein 5.
 
  
   0.856
JUN
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.816
H3AD77_LATCH
JunE proto-oncogene, AP-1 transcription factor subunit.
   
 0.816
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.699
MAPK14
Mitogen-activated protein kinase.
    
 0.694
MAPK11
Mitogen-activated protein kinase.
    
 0.694
MAPK10
Mitogen-activated protein kinase 10.
    
 0.691
MAPK8
Mitogen-activated protein kinase.
    
 0.691
MAPK9
Mitogen-activated protein kinase.
    
 0.690
JUND
BZIP domain-containing protein.
   
 0.661
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.