Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZRN7_LATCHMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)    
Predicted Functional Partners:
SOD2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 
 0.698
ZBTB22
Zinc finger and BTB domain containing 22.
    
 
 0.657
GPX1
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
  
 0.627
FBN1
Fibrillin 1.
      
 0.592
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
      
 0.590
H2ZZW6_LATCH
Protein kinase domain-containing protein.
      
 0.585
ATOX1
Antioxidant 1 copper chaperone.
   
  
 0.578
ATP7B
ATPase copper transporting beta.
      
 0.569
LOC102357450
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 
 0.569
GPX8
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
  
 0.567
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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