STRINGSTRING
IKBKAP protein (Latimeria chalumnae) - STRING interaction network
"IKBKAP" - Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKBKAPInhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation (1142 aa)    
Predicted Functional Partners:
ELP3
Elongator acetyltransferase complex subunit 3 (640 aa)
     
  0.983
ELP2
Elongator acetyltransferase complex subunit 2 (897 aa)
     
  0.979
ELP4
Elongator acetyltransferase complex subunit 4 (438 aa)
     
  0.976
NOC3L
Nucleolar complex associated 3 homolog (S. cerevisiae) (795 aa)
     
      0.761
ALKBH8
alkB, alkylation repair homolog 8 (E. coli) (664 aa)
     
   
  0.675
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae) (275 aa)
     
 
  0.661
FRRS1L
Ferric-chelate reductase 1-like (283 aa)
           
  0.591
POLR1A
Polymerase (RNA) I polypeptide A, 194kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (917 aa)
     
      0.588
ENSLACG00000002247
DNA-directed RNA polymerase subunit ; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (802 aa)
     
      0.588
NFYA
Nuclear transcription factor Y, alpha (340 aa)
       
      0.588
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
Server load: low (7%) [HD]