Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (503 aa)    
Predicted Functional Partners:
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.939
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
    
  0.928
LOC102362971
Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family.
    
  0.928
PIK3R5
Phosphoinositide-3-kinase regulatory subunit 5.
   
 
0.919
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.904
LOC102361424
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.
     
  0.900
GNAI3
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
     
  0.900
LOC102348007
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 0.849
GNB1
G protein subunit beta 1.
     
  0.685
PIK3CD
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.
    
  0.672
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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