Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEPDC1DEP domain containing 1. (823 aa)    
Predicted Functional Partners:
H2ZSE1_LATCH
Uncharacterized protein.
   
  
 0.657
ASPM
Abnormal spindle microtubule assembly.
   
  
 0.606
CENPF
Centromere protein F.
   
  
 0.601
KIF23
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.590
KIF14
Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.585
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.584
MERTK
MER proto-oncogene, tyrosine kinase.
     
 0.577
TTK
TTK protein kinase.
   
  
 0.572
H2ZXS9_LATCH
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
  
 0.566
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
  
 0.566
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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