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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBCCD1TBCC domain containing 1. (563 aa)    
Predicted Functional Partners:
MORN1
MORN repeat containing 1.
      
 0.699
ICMT
Protein-S-isoprenylcysteine O-methyltransferase.
      
 0.685
GINS1
GINS complex subunit 1.
      
 0.685
COPA
Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
      
 0.669
PTPN1
Tyrosine-protein phosphatase non-receptor type.
      
 0.668
ITM2B
Integral membrane protein 2B.
      
 0.663
H2ZX10_LATCH
Uncharacterized protein.
      
 0.627
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
      
 0.622
TLK2
Tousled like kinase 2.
      
 0.612
H3AI54_LATCH
Uncharacterized protein.
   
  
 0.594
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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