STRINGSTRING
LGR5 protein (Latimeria chalumnae) - STRING interaction network
"LGR5" - Leucine-rich repeat containing G protein-coupled receptor 5 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGR5Leucine-rich repeat containing G protein-coupled receptor 5 (625 aa)    
Predicted Functional Partners:
ENSLACG00000012279
Fraser extracellular matrix complex subunit 1 (630 aa)
     
  0.930
PCSK2
Proprotein convertase subtilisin/kexin type 2 (403 aa)
     
  0.925
FURIN
Furin (paired basic amino acid cleaving enzyme) (801 aa)
     
  0.909
PCSK4
Proprotein convertase subtilisin/kexin type 4 (768 aa)
     
  0.904
PCSK7
Proprotein convertase subtilisin/kexin type 7 (760 aa)
     
  0.904
PCSK1
Proprotein convertase subtilisin/kexin type 1 (662 aa)
     
  0.904
PCSK6
Proprotein convertase subtilisin/kexin type 6 (799 aa)
     
  0.904
PCSK5
Proprotein convertase subtilisin/kexin type 5 (616 aa)
     
  0.904
ENSLACG00000018053
Uncharacterized protein (986 aa)
     
  0.904
ENSLACG00000013905
Uncharacterized protein (151 aa)
     
  0.904
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
Server load: low (11%) [HD]