STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLAAT1Phospholipase A and acyltransferase 1. (168 aa)    
Predicted Functional Partners:
GAK
J domain-containing protein.
    
 0.987
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
    
 0.813
DNAJC10
DnaJ heat shock protein family (Hsp40) member C10.
  
 0.794
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.774
BAG3
BCL2 associated athanogene 3.
   
 0.723
GRPEL2
GrpE like 2, mitochondrial; Belongs to the GrpE family.
  
 0.719
GRPEL1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
 0.719
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
  
 
 0.665
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.662
LOC102357218
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
   
 0.653
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.