STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2ZUD6_LATCHB30.2/SPRY domain-containing protein. (170 aa)    
Predicted Functional Partners:
UBE2H
Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.694
HSPB2
Heat shock protein, alpha-crystallin-related, b2; Belongs to the small heat shock protein (HSP20) family.
    
 
 0.661
CREG1
Cellular repressor of E1A-stimulated genes 1.
      
 0.658
SGTA
Small glutamine rich tetratricopeptide repeat containing alpha.
      
 0.549
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 
 0.509
LOC102355547
MACPF domain-containing protein.
  
     0.464
LOC102352844
Uncharacterized protein; Belongs to the beta/gamma-crystallin family.
  
     0.457
NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
      
 0.427
LOC102363479
Uncharacterized protein; Belongs to the beta/gamma-crystallin family.
  
     0.419
SH3KBP1
SH3 domain containing kinase binding protein 1.
   
 
 0.402
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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