Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SDR42E2Short chain dehydrogenase/reductase family 42E, member 2. (204 aa)    
Predicted Functional Partners:
H3AEB4_LATCH
Uncharacterized protein.
      
 0.634
CRAMP1
Cramped chromatin regulator homolog 1.
      
 0.627
NDUFAF2
NADH:ubiquinone oxidoreductase complex assembly factor 2.
      
 0.601
TADA2B
Transcriptional adapter.
      
 0.591
CACNG1
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
      
 0.587
H3A9P1_LATCH
Wu:fc23c09.
      
 0.549
F2RL2
Coagulation factor II thrombin receptor like 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.484
C6
Complement C6.
      
 0.466
H3A0H7_LATCH
Uncharacterized protein.
    
 0.465
H3B493_LATCH
Syncollin, tandem duplicate 3.
      
 0.440
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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