STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)    
Predicted Functional Partners:
PDPK1
3-phosphoinositide dependent protein kinase 1.
    
0.858
RICTOR
RPTOR independent companion of MTOR complex 2.
    
 0.834
MAPKAP1
MAPK associated protein 1.
    
 0.829
MTOR
Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.
    
 0.825
RPS6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
    
 0.818
H3B8U3_LATCH
Serine/threonine-protein kinase TOR.
    
 0.803
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.772
PKN1
Uncharacterized protein.
 
  
 0.699
MLST8
MTOR associated protein, LST8 homolog.
 
  
 0.683
TSC2
TSC complex subunit 2.
    
 0.681
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.